Publications

ALLERGY

Allergic Rhinitis: Market Evolution

Matthew Clark, Ryan Million

Nature Reviews Drug Discovery 2009;8(4):271-272

http://www.nature.com/nrd/journal/v8/n4/full/nrd2762.html

 

CARDIOLOGY

Patients with Non-Valvular Atrial Fibrillation Treated with Warfarin Incur Greater Healthcare Resource Utilization Than Patients Treated with Dabigatran

Martin Zalesak, Kimberly Siu, Kevin Francis, Chen Yu, Hasmik Alvrtsyan, Yajing Rao, David Walker, Stephen Sander, Gavin Miyasato, David Matchar, Herman Sanchez

Circulation: Cardiovascular Quality and Outcomes 2013;6:567-574

http://www.ncbi.nlm.nih.gov/pubmed/?term=23922182

 

Patients with Non-Valvular Atrial Fibrillation Treated with Warfarin Incur Greater Healthcare Resource Utilization Than Patients Treated with Dabigatran

Kevin Francis, Kimberly Siu, Chen Yu, Hasmik Alvrtsyan, Yajing Rao, David Walker, Stephen D Sander, Martin Zalesak, Gavin Miyasato, David Matchar, Herman Sanchez

American College of Preventive Medicine 2013 Conference, February 2013

 

 

The Contribution of Non-Valvular Atrial Fibrillation to Other High-Burden, Chronic Conditions Among the Medicare Population

Scaife, JG, Faulkner, CA, Francis, KM, Gillis, JC, Kokkotos, FK, Walker, DR, Quon, NC, Sander, SD, Wang, Z

American College of Preventive Medicine 2013 Conference, February 2013

Link to Poster

 

Persistence Among Patients with Non-Valvular Atrial Fibrillation Beginning Dabigatran or Warfarin

Kevin Francis, Kimberly Siu, Chen Yu, Hasmik Alvrtsyan, Yajing Rao, David Walker, Stephen Sander, Martin Zalesak, Gavin Miyasato, Herman Sanchez

American Society of Hematology Meeting, December 2012 – Oral Presentation

 

DIAGNOSTICS

 

Is There an Overuse of Computed Tomography (CT) Scanning of Patients in United States Hospitals? A Review of the Evidence

Emma Boswell, Zheng Wang, Fotios Kokkotos, Hong Yu Xiao, Xuan Dong, Hao Tong, Yang Liu

American Statistical Association Conference on Statistical Practice, February 2013
ISPOR 15th European Congress, November 2012

 

Utilizing 2009 CMS Medicare Data To Demonstrate The Overuse Of Computed Tomography Scanning In Medicare Patients

Emma Boswell, Zheng Wang, Fotios Kokkotos, Hong Yu Xiao, Xuan Dong, Hao Tong, Yang Liu

Joint Statistical Meetings, July-Aug, 2012

 

Is there an overuse of computed tomography scanning of patients in US hospitals? A Review of the Evidence Based on the Medicare Claims Database

Fotios Kokkotos, Emma Boswell, Zheng Wang, Grace Xuan Dong

Oral Presentation - Bentley University,  November 2012

 

Impact of genetic diagnostics on drug development strategy

Ryan Million

Nature Reviews Drug Discovery 2006;5(6):459-462

http://www.nature.com/nrd/journal/v5/n6/full/nrd2034.html

 

ENDOCRINOLOGY/ORPHAN

Perceptions and Attitudes of Patients at the Time of Diagnosis With Hypoparathyroidism

Nandini Hadker, Jacqueline Egan, Hjalmar Lagast, Bart L. Clarke

American Association of Clinical Endocrinology (AACE) 22nd Annual Meeting, May 2013

 

 

Impact of Hypoparathyroidism on Patients’ Employment Status, Social Relationships, and Personal Life in the PARADOX Study

Nandini Hadker, Jacqueline Egan, Hjalmar Lagast, Bart L. Clarke

American Association of Clinical Endocrinology (AACE) 22nd Annual Meeting, May 2013

 

 

Clinical Symptoms and Morbidities Reported Among Patients With Hypoparathyroidism: Patients’ Attitudes and Responses About Hypoparathyroidism Toleration Explored (PARADOX Study)

Nandini Hadker, Jacqueline Egan, James Sanders, Hjalmar Lagast, Bart L. Clarke

ENDO The Endocrine Society's 95th Annual Meeting & Expo, June 2013

 

 

FORECASTING

 

Get the Right Assets on the Bus: An Analytical Approach to Managing Portfolio Risk

Leslie Sandberg Orne, Stephen Fleming

CBI Strategic Pipeline Planning & Portfolio Valuation Conference, 2013 – Oral Presentation

 

Forecasting for New Product Launches: Insights into the “Shape of the Curve

Leslie Sandberg Orne

Eyeforpharma Forecasting Summit, 2012 – Oral Presentation

 

Patient Flow Modeling: Integration of Next Generation Primary and Secondary Data to Improve Forecasting Insights

Leslie Sandberg Orne, Cheryl Crawford

Eyeforpharma Forecasting Summit, 2011 – Oral Presentation

 

HEMATOLOGY

 

Blood Transfusion Utilization in Chemotherapy-induced Anemia - An Analysis of US Hospital Inpatient and Outpatient Records

J. Forlenza, A. Herrera, J. Scaife, K. Prifti, T. Foster, E. Boswell

ISPOR 17th Annual International Meeting, June 2012

 

Recent Erythropoiesis Stimulating Agent (ESA) Utilization and Costs in Medicare Patients with Cancer Receiving Chemotherapy (CRC)

Fotios Kokkotos, Robert A. Bailey, Matthew Kerr, Sherlynn Shen, Mekre Senbetta, R. Scott McKenzie

ISPOR 15th Annual International Meeting, May 2010

 

Epoetin Alfa (EPO) Utilization Trends in Medicare Patients with Chronic Kidney Disease (CKD) Not On Dialysis

Fotios Kokkotos, Robert A. Bailey, Matthew Kerr, Sherlynn Shen, Mekre Senbetta, R. Scott McKenzie

National Kidney Foundation Spring Clinical Meeting, April 2010

 

Recent Erythropoiesis Stimulating Agent (ESA) Utilization and Costs in Medicare Patients with Chronic Kidney Disease (CKD)

Fotios Kokkotos, Robert A. Bailey, Matthew Kerr, Sherlynn Shen, Mekre Senbetta, R. Scott McKenzie

National Kidney Foundation Spring Clinical Meeting, April 2010

 

 

HOSPITAL QUALITY SCORES

 

Hospital Quality Scores Versus Medicare Charges and Reimbursement – What is the Association?

Miyasato GS, Wang Z, Meckley LM

ISPOR 19th Annual International Meeting, May 2014

Link to Poster

 

INFECTIOUS DISEASE

 

Medicare Hepatitis C Patients – Are patients under 65 different?

Meckley LM, Wang Z, Miyasato G, Scaife J, Sanchez H

ISPOR 19th Annual International Meeting, May 2014

Link to Poster

 

Prevalence of Hepatic Outcomes Among Medicare Patients Diagnosed with Chronic Hepatitis C Virus Infection

Jillian Scaife, Effie Kuti, Lindsey Acampa, Daina Anhalt, Fotios Kokkotos, Ryan Million, Gavin Miyasato, Stephen Sander, Herman Sanchez, Zheng Wang

ISPOR 18th Annual International Meeting, May 2013

Link to Poster

 

Prevalence of Chronic Hepatitis C Virus and Commonly-Associated Comorbidities within the US Medicare Population

Jillian Scaife, Effie Kuti, Lindsey Acampa, Hasmik Alvrtsyan, Daina Anhalt, Fotios Kokkotos, Ryan Million, Gavin Miyasato, Stephen Sander, Herman Sanchez, Zheng Wang

ISPOR 18th Annual International Meeting, May 2013

Link to Poster

 

Prevalence of Chronic Hepatitis C Virus and Commonly-Associated Comorbidities within a Large US Commercially-Insured Population

Jillian Scaife, Effie Kuti, Lindsey Acampa, Ryan Million, Gavin Miyasato, Zheng Wang, Marcella Lucas, Stephen Sander, Herman Sanchez, Fotios Kokkotos

ISPOR 18th Annual International Meeting, May 2013

Link to Poster

 

Prevalence of Hepatic Outcomes Among Commercially-Insured Patients Diagnosed with Chronic Hepatitis C Virus Infection

Jillian Scaife, Effie Kuti, Lindsey Acampa, Fotios Kokkotos, Ryan Million, Gavin Miyasato, Zheng Wang, Marcella Lucas, Stephen Sander, Herman Sanchez

ISPOR 18th Annual International Meeting, May 2013

Link to Poster

 

Uninsured Chronic Hepatitis C Patients and Their Cost Implications on the Healthcare System

Jillian Scaife, Effie Kuti, Lindsey Acampa, Hasmik Alvrtsyan, Ryan Million, Gavin Miyasato, Zheng Wang, Marcella Lucas, Stephen Sander, Herman Sanchez, Fotios Kokkotos

ISPOR 18th Annual International Meeting, May 2013

Link to Poster

 

Current and Future Disease Progression of the Chronic HCV Population in the United States

Martin Zalesak, Kevin Francis, Alex Gedeon, John Gillis, Kyle Hvidsten, Phyllis Kidder, Linda Li, Derek Martyn, Leslie Sandberg Orne, Amanda Smith, Ann Kwong

PLoS ONE 2013;8(5):e63959.

http://www.ncbi.nlm.nih.gov/pubmed/?term=23704962

 

Recent Trends in the Prevalence of HCV-Infected Medicare Patients and the Associated Cost Burden

Martin Zalesak, Kevin Francis, Ann Kwong, Hong Li, Leslie Orne, Kyle Hvidsten

Academy of Managed Care Pharmacy 24th Annual Meeting, April 2012

 

Current and Future Disease Progression of HCV-Infected Patients Among Different Age Cohorts

Martin Zalesak, Kevin Francis, Ann Kwong, Hong Li, Derek Martyn, Leslie Orne, Amanda Smith, Kyle Hvidsten

Digestive Disease Week, May 2012

 

 

NEUROLOGY/ORPHAN

 

Diagnosis pathway for patients with amyotrophic lateral sclerosis: retrospective analysis of the US Medicare longitudinal claims database

James R. Williams, David Fitzhenry, Lauren Grant, Derek Martyn, Douglas A. Kerr

BMC Neurol. 2013 Nov 4;13:160. doi: 10.1186/1471-2377-13-160.

http://www.ncbi.nlm.nih.gov/pubmed/?term=24499173

 

First Symptoms and the Pathway to Diagnosis for Patients With Amyotrophic Lateral Sclerosis: A Retrospective Analysis of the United States Centers for Medicare & Medicaid Services MedicareLongitudinal Claims Database

James R. Williams, Sarah Kulke, David Fitzhenry, Lauren Grant, Derek Martyn, Douglas A. Kerr

22nd Meeting of the European Neurological Society, June 2012

 

Identifying Providers of Care After a Diagnosis of ALS: A Retrospective Review of the Medicare Claims Database

James R. Williams, David Fitzhenry, Lauren Grant, Derek Martyn, Douglas A. Kerr

11th Annual Northeast Amyotrophic Lateral Sclerosis Consortium (NEALS), October 2012

Link to Poster


ONCOLOGY

 

Prevalence of bone metastases and bone-targeting agent use among solid tumor patients in the United States

Rohini K Hernandez, Avanti Adhia, Sally W Wade, Emily O’Connor, Jorge Arellano, Kevin Francis, Hasmik Alvrtsyan, Ryan P Million, Alexander Liede

Clin Epidemiol. 2015 Jul 17;7:335-345.

http://www.dovepress.com/prevalence-of-bone-metastases-and-bone-targeting-agent-use-among-solid-peer-reviewed-fulltext-article-CLEP#

 

The epigenetics pipeline

Vivian DeWoskin, Ryan Million

Nature Reviews Drug Discovery 2013;12(9):661–662

http://www.nature.com/nrd/journal/v12/n9/full/nrd4091.html

 

Antibody–drug conjugates

Rachel Zolot, Satarupa Basu, Ryan Million

Nature Reviews Drug Discovery 2013;12(4):259-260

http://www.nature.com/nrd/journal/v12/n4/full/nrd3980.html

 

Utilizing 2005-2009 CMS Medicare Data to Demonstrate the Shift of Oncology Patients and Medicare Payment from the Physician Office to the Institutional Outpatient Setting

Zheng Wang, Emma Boswell, Fotios Kokkotos

Joint Statistical Meetings, July-Aug, 2012

 

Estimating Cost of Treatment in Elderly Patients With Colorectal Cancer Using Medicare Data

Fotios Kokkotos, Zheng Wang, Sherlynn Shen, Ya Zhang

ISPOR 16th Annual International Meeting, May 2011

Link to Poster

 

Personalized medicine in oncology: next generation

Alex Chiang, Ryan Million

Nature Reviews Drug Discovery 2011;10(12):895-896

http://www.nature.com/nrd/journal/v10/n12/full/nrd3603.html

 

STRATEGY

 

Tapping the potential of fixed-dose combinations

Tara Herrick, Ryan Million

Nature Reviews Drug Discovery 2007;6(7):513-514

http://www.nature.com/nrd/journal/v6/n7/full/nrd2334.html

 

 

SURGERY

 

What Factors are Associated with Increasing Charges for Major Joint Replacements Between 2008 and 2011?

Chiu GR, Dong X, Wang Z, Meckley LM, Miyasato G

ISPOR 19th Annual International Meeting, May 2014

Link to Poster

 

Factors Associated With Overall and Non-Elective Hospital Readmissions Following Elective Total Knee Replacement

Forlenza J, Boswell E, Zhang Y, Shen S, Doshi D, Kokkotos F, Slabaugh SL

Society for the Advancement of Blood Management Annual Meeting, September 2011

 

Factors Associated With Overall And Non-Elective Hospital Readmissions Following Elective Total Hip Replacement

Forlenza J, Boswell E, Zhang Y, Shen S, Doshi D, Kokkotos F, Slabaugh SL

Society for the Advancement of Blood Management Annual Meeting, September 2011

 

Red Blood Cell Transfusion Utilization in Medicare Discharges with Elective Total Hip Replacement in 2007

Fotios Kokkotos, Robert A. Bailey, Matthew Kerr, Emma Boswell, Mekre Senbetta

American Association of Blood Banks Meeting, October 2010

 

Regional Variation in Red Blood Cell Transfusion Utilization in Elective Total Hip Replacement in Medicare Beneficiaries

Fotios Kokkotos, Robert A. Bailey, Matthew Kerr, Emma Boswell, Mekre Senbetta

Society for the Advancement of Blood Management Annual Meeting, September 2010

 

Regional Variation in Red Blood Cell Transfusion Utilization in Elective Total Knee Replacement in Medicare Beneficiaries

Fotios Kokkotos, Robert A. Bailey, Matthew Kerr, Emma Boswell, Mekre Senbetta

Society for the Advancement of Blood Management Annual Meeting, September 2010